Influence of Propofol and Enflurane on the Neuromuscular Effects of Vecuronium / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 231-234, 1997.
Article
in Korean
| WPRIM
| ID: wpr-103327
ABSTRACT
BACKGROUND:
Previous studies reported the lack of interaction between propofol and neuromuscular blockers. The current study was designed to compare the influence of propofol to that of enflurane on the vecuronium.METHODS:
Forty , either sex, adult patients, scheduled for elective surgery, were randomly assigned to two groups. Patients received either propofol (Group I n=20) or thiopental (Group II n=20) as an induction agent and anesthesia were maintained with either propofol-N2O-O2(Group I) or enflurane- N2O-O2(Group II). Before induction, initial twitch was obtained as a control with supramaximal stimulus. Neuromuscular contraction was monitored continuously and recorded on a relaxograph. Onset time (T0), clinical duration (T25), and recovery index (RI) were measured.RESULTS:
Onset time and clinical duration of vecuronium were not significantly different between two groups. Mean recovery index was 18.5 min and 38.6 min in group Iand II, respectively.CONCLUSION:
These results indicated that propofol, different from enflurane, did not have influence on the recovery index of vecuronium.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thiopental
/
Vecuronium Bromide
/
Propofol
/
Neuromuscular Blockade
/
Enflurane
/
Anesthesia
/
Anesthetics
/
Neuromuscular Agents
/
Neuromuscular Blocking Agents
Limits:
Adult
/
Humans
Language:
Korean
Journal:
Korean Journal of Anesthesiology
Year:
1997
Type:
Article
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