A Clinical Observation on Testicular Tumors / 대한비뇨기과학회지

ABSTRACT

A clinical observation was made on I6 patients with testicular tumors who were admitted to the Department of Urology, Hanyang University Hospital during the period from January, l973 to December, 1984. The following results were obtained. 1. During this period, testicular tumors comprised O.42% of all inpatients and 3.47% of all male G-U tract tumors. 2. The age distribution ranged from 7 months to 56 years old and showed the highest incidence in 1 year to 9 years old. 3. Among the l6 cases with testicular tumors, there were 14 cases of germ cell tumor (2 cases of seminoma with embryonal carcinoma, 8 cases of teratoma, 3 cases of embryonal carcinoma, 1 case of yolk sac tumor) and 2 cases of non-germ cell tumor (all of Leydig cell tumor). 4. The presenting symptoms were painless scrotal mass in l3 cases, painful scrotal mass in 1 case, sexual precocity in 1 case, abdominal mass in 1 case. 5. Preorchiectomy evaluation of serum AFP and HCG was made by radioimmunoassay. Four cases (2 cases of seminoma with embryonal carcinoma, 1 case of embryonal carcinoma, l case of yolk sac tumor) had elevated serum AFP. None had elevated serum HCG. 6. Radical orchiectomy was given for 15 cases. Adjuvant chemotherapy in l case of embryonal carcinoma and VAB-6 combination chemotherapy for recurred tumor in 1 case of seminoma with embryonal carcinoma were performed. 7. Follow-up study was made on 7 cases (1 case of seminoma with embryonal carcinoma, 2 cases of embryonal carcinoma, 1 case of yolk sac tumor, 3 cases of teratoma) of testicular tumors with mean duration of 49 months. Of these 7 cases, 1 case (stage C, embryonal carcinoma) died at l.5 months after orchiectomy and relapse occurred in 1 case of seminoma with embryonal carcinoma and remaining cases are alive without evidence of disease for mean follow-up 64.8 months.