Recent advance in mechanism of epilepsy induced by hypothalamic hamartoma / 中华神经医学杂志

ABSTRACT

Hypothalamic hamartoma is a rare congenital malformation that can cause precocious puberty, epilepsy, cognitive behavior and mental disorders. Hypothalamic hamartoma is the best in vivo model for studying subcortical epilepsy in human. The eplieptogenesis of hypothalamic hamartoma has already been highlight in epilepotology. With deeply exploring and revealing its intrinsic eplieptogenesis of hypothalamic hamartoma, it can expand our research views and ultimately bring new therapies to patients. The latest research progress on epilepotology induced by hypothalamic hamartoma is reviewed as follows.