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Castleman's Disease Presenting with Uveal Effusion Syndrome
Article in English | WPRIM | ID: wpr-103544
Responsible library: WPRO
ABSTRACT
We report a rare case of multicentric Castleman's disease that presented with ophthalmic involvement, along with a review of the literature. A 63-year-old male presented with decreased visual acuity in both eyes. Both eyes had serous elevations of the retinas with shifting subretinal fluid and annular choroidal detachment. No retinal breaks were found. Laboratory tests revealed pancytopenia, hypergammaglobulinemia, and an increased erythrocyte sedimentation rate. Chest and abdominal computed tomographies showed multiple lymphadenopathies in the mediastinum, abdomen, and in both inguinal areas. Histological examination of the inguinal lymph node biopsy was consistent with Castleman's disease. After combination chemotherapy, the serous elevations of both retinas and the annular choroidal detachments of both eyes disappeared. Ophthalmic involvement in Castleman's disease is very rare, and to the authors' knowledge, this is the first report of ophthalmic involvement of Castlemans's disease in Korea.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Syndrome / Uveal Diseases / Aged / Humans / Male / Magnetic Resonance Imaging / Fluorescein Angiography / Choroid Diseases / Castleman Disease / Treatment Outcome Language: English Journal: Korean Journal of Ophthalmology Year: 2010 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Syndrome / Uveal Diseases / Aged / Humans / Male / Magnetic Resonance Imaging / Fluorescein Angiography / Choroid Diseases / Castleman Disease / Treatment Outcome Language: English Journal: Korean Journal of Ophthalmology Year: 2010 Type: Article