Recent advance in role of C-type lectin-like receptor 2 in acute ischemic stroke / 中华神经医学杂志
Chinese Journal of Neuromedicine
; (12): 948-951, 2021.
Article
in Zh
| WPRIM
| ID: wpr-1035509
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WPRO
ABSTRACT
Acute ischemic stroke (AIS) is one of the main causes of death and disability in adults, which has brought a heavy burden to society and families. The intertwined process of thrombosis and thrombus inflammation plays a key role in the pathogenesis of AIS. The latest studies find that C-type lectin-like receptor 2 (CLEC-2) may play an important role in cerebral ischemia/reperfusion injury in mice by promoting thrombus inflammation, and its level is related to the progression of AIS and prognoses of patients with AIS. The author reviews the physiological and pathological effects of CLEC-2 and its related research progress in AIS, with a view to provide new research evidences for the occurrence and development of AIS and related treatments.
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Neuromedicine
Year:
2021
Type:
Article