The Effect of Intravitreal Bevacizumab in Patients with Acute Central Serous Chorioretinopathy
Korean Journal of Ophthalmology
;
: 155-158, 2010.
Article
in English
| WPRIM
| ID: wpr-103551
ABSTRACT
PURPOSE:
To evaluate the effect of intravitreal bevacizumab injection (IVBI) in acute central serous chorioretinopathy (CSC) patients.METHODS:
Patients with acute CSC received IVBI (1.25 mg/0.05 mL) or observation by randomization. Twelve eyes in each group completed 6 months of regular follow-up and were ultimately included in this study. Each patient was assessed using best corrected visual acuity measurements, fluorescein angiography, and optical coherence tomography at baseline and had regular follow-ups after treatment.RESULTS:
All patients showed improvements in visual acuity and fluorescein angiographic leakage and had resolution of their neurosensory detachment following treatment. There were no significant differences in visual acuity, central retinal thickness, or remission duration between the IVBI group and the control group at baseline or after treatment (p>0.05).CONCLUSIONS:
Intravitreal bevacizumab showed no positive effect in acute CSC patients compared to the observation group, and there were no adverse effects of treatment. Further investigation will be helpful to understand this therapy in patients with CSC.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Vitreous Body
/
Capillary Permeability
/
Visual Acuity
/
Acute Disease
/
Follow-Up Studies
/
Treatment Failure
/
Vascular Endothelial Growth Factor A
/
Central Serous Chorioretinopathy
/
Injections, Intraocular
/
Antibodies, Monoclonal
Type of study:
Controlled clinical trial
/
Observational study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Korean Journal of Ophthalmology
Year:
2010
Type:
Article
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