Recent advance in effect and dietary intervention of PM2.5 on Parkinson's disease / 中华神经医学杂志

ABSTRACT

Parkinson's disease (PD) is the second largest neurodegeneration disease in the world, characterized by tremors, rigidity and bradykinesia. Fine particulate matter (PM2.5) is a kind of airborne particulate matters whose diameter≤2.5 μm. Epidemiological studies have shown that PM2.5 is associated with PD, and both short-term and long-term exposures to PM2.5 can increase PD risk. However, few relevant studies and still unclear mechanism are noted; therefore, this article reviews the epidemiological studies, mechanism and dietary intervention strategies of PM2.5 and PD.