Antimicrobial Prophylaxis Using a 2nd Generation Cephalosporin after Laparoscopic Colorectal Resection: A Randomized Trial of 1-day vs. 3-day
Journal of the Korean Surgical Society
;
: 385-389, 2010.
Article
in Korean
| WPRIM
| ID: wpr-10361
ABSTRACT
PURPOSE:
We performed this study to compare 1-day group using a 2nd generation cephalsporin with 3-day group for evaluating hospital acquired infection.METHODS:
The patients underwent laparoscopic colorectal surgery at Korea University Medical Center Anam Hospital, from August, 2007 to June, 2008. They were randomly allocated to 2 groups 1-day or 3-day group. A 2nd generation cephalosporin was administered within 1 hour before surgery with 12-hour intervals. In cases of suspected infection, further studies were done to identify infection.RESULTS:
The study included 154 patients (1-day group - 78, vs. 3-day group - 76). No differences were noted between the 2 groups in age, body mass index, smoking, diabetes mellitus, corticosteroid-use were noted. Gender (P=0.011) and mean operative time (P=0.047) between the 2 groups were different. The preventive rates of infection were 87.18% in the 1-day group compared with 82.89% in the 3-day group (P=0.456).CONCLUSION:
Our prospective randomized control study concluded that there were no differences between the 1-day and 3-day group in hospital acquired infection. We could come to the conclusion that 1-day antimicrobial agent in laparoscopic colorectal surgery would be adequate in preventing infection.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Smoke
/
Smoking
/
Body Mass Index
/
Prospective Studies
/
Colorectal Surgery
/
Diabetes Mellitus
/
Academic Medical Centers
/
Operative Time
/
Korea
Type of study:
Controlled clinical trial
/
Observational study
Limits:
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Journal of the Korean Surgical Society
Year:
2010
Type:
Article
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