Clinical Comparasion of Induced Labor with Dinoprostone Misoprostol and Oxytocin / 中国现代医生

ABSTRACT

Objective To comparatively study on clinical effectiveness of dinoprostone(propess). Misoprostol and oxytocin in promoting cervical ripening and induced lbor. Methods A tolal of 180 patients with singleton gestation and with indications for labor induction were randomly assigned to 3 groups, respectively. Women were randomiged to receive propess 10mg(dinoprostone group) or misoprostal 25ug (misoprostal group) in posterion vaginal fomix and intravenous 0.5%～1% oxytocin (oxytocin group). Results Propess was better than oxytocin in promoting cervical ripening. The time to labor starting, membrane rapture and delivery was significantly shorter in the propess group than in the oxytoein group after applying medicine 24h later,the successful induced labor rate were 80.0% and 20.0%(P <0.01). The effectiveness of the propess group and the misoprostol group in promoting cervical ripening and induced labor was similar(P>0.05).Conclusion Propess can be used in promoting cervical ripening and induced labor safely and effectively.