Study on the postoperative analgesic effect of dezocine and sufentanil in patients with colorectal cancer / 中国现代医生

ABSTRACT

Objective To investigate the postoperative analgesic effect of dezocine and sufentanil in patients with col-orectal cancer. Methods Sixty-eight cases with colon cancer, rectal cancer undergoing radical operation in our hospital from January 2011 to June 2013, were randomLy divided into control group and observation group, 34 patients in each group, the patients in control group were given sufentanil analgesia after surgery, and patients in the observation group were given dezocine and sufentanil for analgesia. The VAS and Ramsay sedation score in 2h, 6h, 12h, 24h, 48h and the incidence ratio of adverse reaction during analgesia were compared in two groups. Results There was no statistical significance in the difference of the two groups of sex ratio, age distribution, body weight, ASA classification (P>0.05);there was no significnt difference in VAS scores between the two groups at different time points (P>0.05);There were statistically significant in differences of Ramsay scores among different time points of two groups (P<0.05);There were statistically significant in differences of the incidence ratio of adverse reaction of two groups during analgesia (drowsiness, nausea and vomiting, urinary retention) (P<0.05). Conclusion Analgesic effect of using dezocine and sufentanil with less adverse reaction, good safety is obvious better than sufentanil only in the patients with colorectal cancer after operation, and is worth the clinical promotion.