The effect of valsartan combined with amlodipine besylate in treatment of elderly hypertension curative effect observation of 32 cases / 中国现代医生

ABSTRACT

Objective To evaluate the effect of valsartan combined with amlodipine besylate in treatment of senile hy-pertension. Methods A total of 64 cases (over 60 years old) elderly patients with hypertension from January 2014 to January 2015 in our hospital as the object of study, the drug during the two groups of patients had no other effects on blood pressure, control group was given amlodipine besylate 5 to 10 mg orally, 1 time a day;the observation group with oral valsartan 80 mg, 1 time a day, for 12 weeks, 4 weeks for 1 course of treatment, changes of blood pressure were monitored before and after each course of treatment. Results The total effective rate in the observation group after treatment, was 90.6%, total effective rate in control group was 71.9% after treatment, the efficacy of two groups were compared, the difference was statistically significant (P<0.05). The observation group after combination of systolic blood pressure, diastolic blood pressure decreased significantly, the difference was statistically significant (P<0.05). The control group after combination of systolic blood pressure, diastolic blood pressure decreased significantly, the differ-ence was statistically significant(P<0.05). Compared with the control group, the observation group after treatment SBP, DBP decreased more significantly, the difference was statistically significant (t=2.532, 3.526, P<0.05). Conclusion Val-sartan combined with amlodipine besylate in treatment of elderly hypertension curative effect is better than single drug effect, can effectively control the blood pressure level, and the security is better.