The diagnostic value of high-resolution magnetic resonance in young stroke patients / 中风与神经疾病杂志

ABSTRACT

@#This study is aimed to explore the value of high-resolution magnetic resonance （HRMRI） in the diagnosis of the etiology of stroke in young adults. Methods We retrospectively enrolled ischemic stroke or transient ischemic attack patients who ≤55 years old admitted in Peking Union Medical College Hospital from January 1，2016 to December 31，2020.Patients were separated into two groups：with or without HRMRI. After collecting the baseline data，clinical features，and imaging characteristics，we explore the differences in the clinical characteristics，the etiology of stroke，and the proportion of cryptogenic stroke between the two groups. The changes of cryptogenic stroke proportion in the HRMRI group before and after HRMRI were further calculated，and the changes of the revised diagnosis were also obtained. Results A total of 155 cases were included in the study. Of those，73 cases （47.1%） underwent HRMRI，while 82 cases （52.9%） did not. HRMRI group was slightly younger than the non-HRMRI group （40.36 VS 43.89，P=0.026），while there were no significant differences in gender，risk factors，and family history. The cryptogenic stroke proportion in the HRMRI group was lower than that in the group without HRMRI （16.4% VS 26.8%，P=0.119）.29% of patients were corrected or make more accurate the diagnosed with the help of HRMRI，reducing cryptogenic stroke by 7%. The changes in the etiology diagnosis mainly from cryptogenic stroke to atherosclerosis disease （5，5/20），and also from other vascular diseases such as arterial dissection to atherosclerosis disease （5，5/20）.Conclusion With HRMRI，nearly one-third of young stroke has revised or accurate for their diagnosis，and the remaining has confirmed for their diagnosis. This technique should be widely used in young stroke patients.