The value of 18 F ⁃FDG PET/CT dynamic imaging in the diagnosis of primary hepatocellular carcinoma with liver metastases / 安徽医科大学学报

ABSTRACT

Objective @#To explore the value of 18 F ⁃FDG PET/CT dynamic imaging in the diagnosis of primary liver cancer and liver metastases.@*Methods @#In this study , the data of 94 patients with hepatic malignant lesions [hepatocellular carcinoma group (25 cases) , cholangiocellular carcinoma group (27 cases) , and liver metastases group (42 cases)] imaged by whole⁃body dynamic 18 F ⁃FDG PET/CT were used as the research subjects , and the methods of (ANOVA) and subjects ′ working characteristic curves (ROC) were applied to examine the patients with liver malignant tumours of different pathological types SUV max , MRFDG , TBR and d max were statistically analysed as imaging features. @*Results @#Among 94 patients , the differences in SUV max , MRFDG , TBRSUV max and TBRMRFDG were statistically significant in the hepatocellular carcinoma , cholangiocellular carcinoma and hepatic metastasis groups (SUV max : F = 48. 773 , P < 0. 001 ; MRFDG : F = 26. 334 , P < 0. 001 ; TBRSUV : F = 41. 314 , P < 0. 001 ; TBRMRFDG : F = 20. 821 , P < 0. 001) . The AUCs for the differential diagnosis of primary hepatocellular carcinoma and hepatic metastases for SUV max , MRFDG , TBRSUV max , and TBRMRFDG were 0. 836 , 0. 851 , 0. 827 , and 0. 847 , respectively. There was a positive correlation between SUV max , MRFDG , and the hepatic malignant lesions ′ There was a positive correlation between SUV max , MRFDG and the maximum diameter d max (SUV max : r = 0. 4 , P < 0. 05 ; MRFDG :r = 0. 2 , P < 0. 05) , and the difference was statistically significant. @*Conclusion @#18 F ⁃FDG PET/CT dynamic imaging has good differential diagnostic efficacy in different pathological types of liver malignant tumors. There is a positive correlation between SUV max , MRFDG and d max in different pathological types of liver malignant tumors.