Effect of hypokalemia and hyponatremia on short-term prognosis in patients with acute ischemic stroke / 中风与神经疾病杂志

ABSTRACT

@#Objective　To study the effects of hypokalemia and hyponatremia on the short-term prognosis of patients with acute ischemic stroke. Methods　A total of 108 patients who were admitted to Fushun Central Hospital and received intravenous thrombolysis from November 2018 to May 2019 were selected，including acute ischemic stroke patients（45 cases） and acute ischemic brain. Patients with stroke with hyponatremia（36 cases） and acute ischemic stroke with hypokalemia（27 cases）. The three groups of patients were compared with the NIHSS score before thrombolysis，24 hours after thrombolysis，and 3 days after thrombolysis. Are there differences in mRs scores and bleeding conversion rates at 14 days? The hypokalemia component was group A（mild hypokalemia），group B（moderate hypokalemia），and group C（severe hypokalemia），and the hyponatremia component was group a（mild hyponatremia）. Groups B，B（moderately low sodium），and C（severe low sodium），compared the NIHSS scores before thrombolysis，24 hours after thrombolysis，and 3 days，and whether there were differences in mRs scores 14 days after thrombolysis. Results　There was no significant difference in the NIHSS scores before thrombolysis in the three groups（P>0.05）. The NIHSS scores of the three groups decreased after 24 hours，3 days，and the mRs scores after 14 days，with hyponatremia. The decline in thrombolytic patients was not as good as the other two groups，and the difference was statistically significant（P<0.05）. There was no significant difference in bleeding conversion rates among the three groups（P>0.05）. There were no significant differences in the NIHSS scores before thrombolysis，24 hours after thrombolysis，and 3 days，and the mRs scores at 14 days after thrombolysis（P>0.05）. Comparing the three groups a，b，and c，there were significant differences in NIHSS scores at 24 hours and 3 days after thrombolysis，and mRs scores at 14 days after thrombolysis（P<0.05）. Conclusion　Hyponatremia is associated with acute ischemic stroke The short-term prognosis of thrombolytic patients has adverse effects，and the lower the blood sodium concentration，the greater the impact.