Novalis Shaped Beam Radiation Treatment for Craniopharyngiomas
Journal of Korean Neurosurgical Society
;
: 245-248, 2006.
Article
in English
| WPRIM
| ID: wpr-104002
ABSTRACT
OBJECTIVE:
To evaluate the effectiveness of Novalis shaped beam radiation treatment as an adjuvant treatment in patients with craniopharyngiomas.METHODS:
We reviewed 8 patients with craniopharyngiomas who had recurring tumors during follow-up or had residual lesions after primary surgery. Three of 8 patients were found to have recurrence after gross total excision of the tumor and 5 patents had residual lesions after subtotal resection. All patients were treated with fractionated stereotactic radiation treatment(FSRT) using Novalis system. The mean age of patients was 28 years (range 16~52). The median irradiation dose per fraction was 1.7Gy (range 1.7~2.0). The median fraction number was 23 (range 15~25), and the median total dose was 39.1Gy (range 25.5~42.5). Follow-up included MR imaging, and ophthalmologic and endocrine examinations.RESULTS:
The median follow-up period was 23 months (range 12~43). The local tumor control rate was 87.5%. One patient had a recurring tumor, in which cystic change developed 2 months after FSRT. Four patients showed a decrease in size of their tumor, while 3 patients remained stable. Seven out of 8 patients had hormonal dysfunction that remained unchanged after initial surgery. No further progression of visual impairment was observed.CONCLUSION:
FSRT using Novais system is effective and safe for the treatment of recurring or residual craniopharyngiomas without toxicity like optic neuropathy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Vision Disorders
/
Magnetic Resonance Imaging
/
Optic Nerve Diseases
/
Follow-Up Studies
/
Craniopharyngioma
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Journal of Korean Neurosurgical Society
Year:
2006
Type:
Article
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