Impact of an Antimicrobial Stewardship Program on Unnecessary Double Anaerobic Coverage Prescription / 감염과화학요법
Infection and Chemotherapy
;
: 111-116, 2015.
Article
in English
| WPRIM
| ID: wpr-104518
ABSTRACT
BACKGROUND:
Co-administration of two or more antimicrobials with anti-anaerobic activity is not recommended except in certain circumstances. We therefore conducted an intervention to reduce unnecessary double anaerobic coverage (DAC) prescription. MATERIALS ANDMETHODS:
The intervention consisted of education using an institutional intranet and prospective audits and feedback provided through collaboration between a pharmacist and an infectious diseases physician in Seoul National University Bundang Hospital, a tertiary hospital in Seongnam, Republic of Korea, in 2013. The study period was 1 year which contained 6 months of pre-intervention period and 6 months of intervention period. To estimate the overall effect of the intervention, we compared the monthly number of patients receiving unnecessary DAC for more than 3 days and the proportion of patients receiving unnecessary DAC for more than 3 days among all patients receiving DAC.RESULTS:
The average monthly number of patients receiving unnecessary DAC for more than 3 days after screening decreased by 73.9% in the intervention period from 26.8 to 7.0. Wilcoxon rank sum test revealed there was a significant statistical difference in the monthly number of patients receiving unnecessary DAC for more than 3 days (P = 0.005). The proportion of patients receiving unnecessary DAC for more than 3 days after screening among all patients identified as receiving necessary or unnecessary DAC also decreased by 67.8% in the intervention period from 42.3% to 13.6% (P < 0.001).CONCLUSION:
The multidisciplinary antimicrobial stewardship program with combined methods reduced unnecessary DAC prescription successfully.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacists
/
Bacteria, Anaerobic
/
Computer Communication Networks
/
Mass Screening
/
Communicable Diseases
/
Cooperative Behavior
/
Education
/
Prescriptions
/
Republic of Korea
/
Inappropriate Prescribing
Type of study:
Screening study
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Infection and Chemotherapy
Year:
2015
Type:
Article
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