Effects of one-time and two-time intra-articular injection of hyaluronic acid sodium salt after joint surgery in dogs
Journal of Veterinary Science
;
: 215-222, 2013.
Article
in English
| WPRIM
| ID: wpr-104696
ABSTRACT
Thirty-one dogs with patellar luxation (grades 2 and 3) were categorized into three groups. Group 1 (G.1; n = 12) had sodium hyaluronate (SHA) intra-articularly injected into the stifle joint that received surgery. Group 2 (G.2; n = 10) received SHA twice first after surgery and then 1 week later. Group 3 (G.3; n = 9) served as a control, without injection. Blood was collected before injection and then once a week for 4 weeks after injection for evaluation of chondroitin sulfate (CS-WF6) and hyaluronan (HA). The results revealed significantly (p 0.05) was observed in serum biomarkers between G.1 and G.2. In conclusion, intra-articular injection with SHA after joint surgery may improve homeostasis of the joint, retarding the process of OA.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Stifle
/
Blood Chemical Analysis
/
Enzyme-Linked Immunosorbent Assay
/
Chondroitin Sulfates
/
Osteoarthritis, Knee
/
Dose-Response Relationship, Drug
/
Viscosupplements
/
Hyaluronic Acid
/
Injections, Intra-Articular
Limits:
Animals
Language:
English
Journal:
Journal of Veterinary Science
Year:
2013
Type:
Article
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