A case of insulin autoimmune syndrome / 대한내과학회지
Korean Journal of Medicine
;
: S122-S126, 2009.
Article
in Korean
| WPRIM
| ID: wpr-105017
ABSTRACT
Insulin autoimmune syndrome is an uncommon cause of hypoglycemia. According to the type of antibody, it can be classified as caused by insulin or insulin receptor autoantibodies. Generally, insulin autoimmune syndrome develops following exposure to exogenous insulin or sulfhydryl medications, although insulin or insulin receptor antibody may also occur spontaneously. We treated a 54-year-old woman who developed spontaneous hypoglycemia. The patient had repeated hypoglycemia despite the infusion of dextrose solution. Her serum insulin, c-peptide, and insulin autoantibody were elevated, even during the hypoglycemic periods. Insulin receptor autoantibody and HLA-cw4/B62/DR4 were positive. After steroid and diazoxide treatment, the hypoglycemic symptoms improved gradually. No further hypoglycemic episodes occurred after tapering the medication over 1 year. We present a case of insulin autoimmune syndrome with positive insulin and insulin receptor autoantibodies.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Autoantibodies
/
C-Peptide
/
Receptor, Insulin
/
Diazoxide
/
Glucose
/
Hypoglycemia
/
Insulin
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2009
Type:
Article
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