Comparison of disinfective power according to application order of 70% isopropyl alcohol and 10% povidone-iodine / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 519-524, 2013.
Article
in English
| WPRIM
| ID: wpr-105214
ABSTRACT
BACKGROUND:
Many disinfectants have been used clinically in both single and combination applications, but there have been few studies on disinfective power according to sterilization sequence when using a combination of disinfectants. The purpose of this study was to evaluate the disinfective power of a combination of 70% isopropyl alcohol and 10% povidone-iodine (PVP-I) according to sterilization sequence.METHODS:
Two hundred healthy volunteers were recruited. Subjects were disinfected with a combination of 70% isopropyl alcohol and 10% PVP-I on both forearms, in varying sequence. The AP group included disinfections on the left forearm with isopropyl alcohol first followed by 10% PVP-I, while the PA group included disinfections on the right forearm with same disinfectants in reverse order. Skin cultures were obtained using cotton swabs 3 min after application of each disinfectant, and then were inoculated on blood agar plates for bacterial culture. Cultures were incubated at 37degrees C under aerobic conditions for 48 hours.RESULTS:
There was no significant difference in the number of positive cultures after the 1st disinfection (AP, 45; PA, 36, P = 0.262) or the 2nd disinfection (AP, 6; PA, 13, P = 0.157), suggesting that there is no relationship between disinfective power and the sequence of the disinfectants used. The number of positive cultures significantly decreased after the 2nd disinfection (P < 0.01), however.CONCLUSIONS:
There was no significant difference in disinfective power according to sterilization sequence with 70% isopropyl alcohol and 10% PVP-I in healthy volunteers. The combination of 70% isopropyl alcohol and 10% PVP-I was more effective than disinfection with a single agent regardless of sterilization sequence.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Povidone-Iodine
/
Skin
/
Sterilization
/
Disinfection
/
2-Propanol
/
Agar
/
Disinfectants
/
Healthy Volunteers
/
Forearm
Language:
English
Journal:
Korean Journal of Anesthesiology
Year:
2013
Type:
Article
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