Clinical Manifestation and Predisposing Factors of Infectious Keratitis Following Penetrating Keratoplasty in Korean Patients
Journal of the Korean Ophthalmological Society
;
: 504-509, 2010.
Article
in Korean
| WPRIM
| ID: wpr-105764
ABSTRACT
PURPOSE:
To report the clinical manifestation, predisposing factors, microbiological profiles and treatment outcome of infectious keratitis following penetrating keratoplasty (PK).METHODS:
Medical records of the post-PK patients later diagnosed with culture-positive keratitis, between January 2003 and June 2008 at our hospital were retrospectively reviewed.RESULTS:
Among 228 eyes of 226 patients who previously had PK, 18 eyes (7.89%) of 16 patients developed microbial keratitis. Fifteen patients had a bacterial infection, of which a Streprococcus species was the most common causative microorganism (6 eyes, 33.3%). Three eyes had fungal infection; one case was co-infected with bacteria. Six eyes (33.3%) presented with a suture-related problem, and sixteen eyes (88.9%) had been using topical glaucoma medications. The suture-related problem and use of glaucoma medication were significantly associated with the development of infectious keratitis (p=0.040 and 0.013, respectively). Remission was achieved in all cases within the mean duration of 2.47 months after treatment initiation. However, visual improvement was not achieved in 11 eyes (68.7%) due to graft opacity.CONCLUSIONS:
Early identification of predisposing factors and appropriate management at an early stage may prevent the occurrence of graft infection and improve graft survival.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Bacteria
/
Bacterial Infections
/
Glaucoma
/
Medical Records
/
Retrospective Studies
/
Keratoplasty, Penetrating
/
Treatment Outcome
/
Cornea
/
Transplants
/
Eye
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Ophthalmological Society
Year:
2010
Type:
Article
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