Acute renal failure and delayed neuropathy due to anti-freeze ingestion / 대한내과학회지
Korean Journal of Medicine
;
: 64-70, 2001.
Article
in Korean
| WPRIM
| ID: wpr-105796
ABSTRACT
Antifreeze contains ethylene glycol up to ninty five percent. Ethylene glycol is colorless, odorless, sweet-tasting and water-soluble compound and has been widely used as a chemical solvent. Ethylene glycol has been reported as a common cause of incidental poisoning all over the world because of its easy access. However, in Korea, it is not easy to find statistical references on incidences of ethylene glycol intoxication, except two reported cases. Ethylene glycol itself is not toxic substance. But, many other daughter metabolites are very toxic and lethal. Acid metabolites among them can cause metabolic acidosis. Oxalate, end-product of ethylene glycol, is quickly transformed to calcium oxalate crystals, which precipitate in body tissues such as brain, kidney, heart, liver, and pancreas. We report a case of acute renal failure and neuropathy due to ethylene glycol intoxication along with a review of toxic effects of ethylene glycol.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pancreas
/
Poisoning
/
Acidosis
/
Brain
/
Calcium Oxalate
/
Nuclear Family
/
Incidence
/
Ethylene Glycol
/
Eating
/
Acute Kidney Injury
Type of study:
Incidence study
/
Prognostic study
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2001
Type:
Article
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