Demineralized Bone Matrix, as a Graft Enhancer of Auto-Local Bone in Posterior Lumbar Interbody Fusion
Asian Spine Journal
;
: 129-137, 2014.
Article
in English
| WPRIM
| ID: wpr-106229
ABSTRACT
STUDY DESIGN:
A case controlled study with prospective data collection.PURPOSE:
To evaluate the early influence and the final consequence of demineralized bone matrix (DBM) on auto-local bone as a graft enhancer in posterior lumbar interbody fusion (PLIF). OVERVIEW OF LITERATURE DBM is known as an osteoinductive material; however, it has not been clearly recognized to enhance auto-local bone with a small amount.METHODS:
Patients who had a PLIF were allocated into two groups. Group I (70 cases) used auto-local bone chips and group II (44 cases) used DBM as an additive to auto-local bone, 1 mL per a segment. Group selection was alternated. Early assessment was performed by computed tomography at 6 months and final assessment was done by simple radiography after 24 months at least. The degree of bone formation was assessed by 4 grade scale.RESULTS:
The subjects of both groups were homogenous and had similar Oswestry Disability Index at final assessment. The ratio of auto-local bone chips and DBM was 61. The degree of bone formation at 6 months after surgery was superior in group II. However, there was no significant difference between the two groups at the final assessment.CONCLUSIONS:
DBM was not recognized to enhance auto-local bone with small amount.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteogenesis
/
Bone Matrix
/
Radiography
/
Case-Control Studies
/
Data Collection
/
Prospective Studies
/
Transplants
Type of study:
Diagnostic study
/
Observational study
Limits:
Humans
Language:
English
Journal:
Asian Spine Journal
Year:
2014
Type:
Article
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