Glioblastoma in a Patient with Neurofibromatosis Type 1: A Case Report and Review of the Literature
Brain Tumor Research and Treatment
;
: 36-38, 2014.
Article
in English
| WPRIM
| ID: wpr-106234
ABSTRACT
Neurofibromatosis type 1 (NF1) is an autosomal dominantly inherited familial tumor syndrome. Benign tumors such as pilocytic astrocytoma, optic glioma make up the majority of intracranial neoplasms in patients with NF1. There have only been a handful of cases in which adult glioblastoma presented with NF1. A 32-year-old male presented with headache and radiological studies showing a high grade intra-axial tumor. The patient underwent gross total surgical excision and the pathology revealed glioblastoma. After the surgery, he received concomitant chemo-radiotherapy with temozolomide and adjuvant temozolomide chemotherapy. We report a NF1 patient who developed glioblastoma and reviewed related articles.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Astrocytoma
/
Brain Neoplasms
/
Neurofibromatosis 1
/
Glioblastoma
/
Optic Nerve Glioma
/
Drug Therapy
/
Hand
/
Headache
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
Brain Tumor Research and Treatment
Year:
2014
Type:
Article
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