A Case of Goodpasture's Syndrome / 대한신장학회잡지

ABSTRACT

Goodpasture's syndrome is an autoimmune disease characterized by rapid progressive glomerulonephritis, alveolar hemorrhage and autoantibody to the NC1 domain of the alpha 3 chain of type IV collagen (anti-glomerular basement membrane antibody). It was common in Europe with peak incidence at third decades. However, Goodpasture's syndrome was reported only three cases in Korea. We reported a case of Goodpasture's syndrome in a 34 year old male. He admitted our hospital due to dyspnea and hemoptysis. We made diagnosis by detection of Anti-GBM Ab and biopsy of kidney. He was treated with hemodialysis, plasma exchanges and immunosuppressive agents. However, his renal function was not recovered. Currently, he is receiving regular hemodialysis.