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Association of Bone Mineral Density With Hearing Impairment in Postmenopausal Women in Korea
Clinical and Experimental Otorhinolaryngology ; : 319-325, 2016.
Article in English | WPRIM | ID: wpr-106636
ABSTRACT

OBJECTIVES:

Previous studies examining the association between osteoporosis (OP) and hearing loss (HL) have shown conflicting results. The objective of the present study was to examine the association between hearing impairment and OP in postmenopausal women, using appropriate statistical analyses.

METHODS:

Total 1,009 participants were included in the current study. The propensity score matched (PSM) cohort was defined as the cohort including participants diagnosed with OP and participants without OP. Three statistical models were developed where model 1 was unadjusted, model 2 included age, and model 3 included age, body mass index, alcohol intake, smoking habit, diabetes mellitus, hypertension, high density lipoprotein cholesterol, triglyceride level, vitamin D, and alkaline phosphatase.

RESULTS:

There were 776 and 233 participants in the groups diagnosed without and with OP, respectively. For propensity score matching, 233 pairs were selected from the 776 participants without OP. In the total cohort, using statistical models 2 and 3, no significant difference in the four hearing thresholds was identified between the 2 groups. Logistic regression indicated that, in model 3, participants with OP had a 1.128 (P=0.323) increased risk HL. A significant HL risk was not observed in participants with OP. Using statistical model 3, there were no significant associations among lumbar spine or femoral neck T-scores and changes in the hearing thresholds. In the PSM cohort, statistical models also showed similar results.

CONCLUSION:

The current study did not demonstrate and association between bone mineral density and hearing impairment in the study population of postmenopausal Korean women.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Osteoporosis / Smoke / Spine / Triglycerides / Vitamin D / Smoking / Body Mass Index / Bone Density / Logistic Models / Cohort Studies Type of study: Etiology study / Incidence study / Observational study / Prognostic study / Risk factors Limits: Female / Humans Country/Region as subject: Asia Language: English Journal: Clinical and Experimental Otorhinolaryngology Year: 2016 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Osteoporosis / Smoke / Spine / Triglycerides / Vitamin D / Smoking / Body Mass Index / Bone Density / Logistic Models / Cohort Studies Type of study: Etiology study / Incidence study / Observational study / Prognostic study / Risk factors Limits: Female / Humans Country/Region as subject: Asia Language: English Journal: Clinical and Experimental Otorhinolaryngology Year: 2016 Type: Article