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Histopathological and immunohistochemical findings of primary and metastatic medullary thyroid carcinoma in a young dog
Journal of Veterinary Science ; : 449-453, 2014.
Article in English | WPRIM | ID: wpr-106729
ABSTRACT
This report describes the gross, histological, and immunohistochemical features of medullary thyroid carcinoma (MTC) with pulmonary metastases in a young dog. Sheets of pleomorphic cells supported by fibrous stroma characterized the primary mass, while metastatic nodules had a neuroendocrine pattern. Despite differing histologic features, all masses showed marked immunoreactivity against calcitonin and multiple neuroendocrine markers consistent with MTC. Although MTC is a well-recognized entity, it may be difficult to distinguish this mass from other thyroid neoplasms, necessitating immunohistochemical characterization.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Thyroid Neoplasms / Laryngeal Neoplasms / Carcinoma, Neuroendocrine / Dog Diseases / Lung Neoplasms / Neoplasm Metastasis Type of study: Diagnostic study Limits: Animals Language: English Journal: Journal of Veterinary Science Year: 2014 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Thyroid Neoplasms / Laryngeal Neoplasms / Carcinoma, Neuroendocrine / Dog Diseases / Lung Neoplasms / Neoplasm Metastasis Type of study: Diagnostic study Limits: Animals Language: English Journal: Journal of Veterinary Science Year: 2014 Type: Article