Dietary germanium biotite supplementation enhances the induction of antibody responses to foot-and-mouth disease virus vaccine in pigs
Journal of Veterinary Science
;
: 443-447, 2014.
Article
in English
| WPRIM
| ID: wpr-106730
ABSTRACT
We evaluated the potential ability of germanium biotite (GB) to stimulate the production of antibodies specific for foot-and-mouth disease virus (FMDV). To this aim, we measured the total FMDV-specific antibody responses and IgM production after vaccination against FMD both experimentally and in the field. GB supplementation with FMDV vaccination stimulated the production of anti-FMDV antibodies, and effectively increased IFN-gamma and TNF-alpha levels. These results suggest that GB may be a novel alternative feed supplement that can serve as a boosting agent and an immunostimulator for increasing the efficacy of FMDV vaccination in pigs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Swine
/
Swine Diseases
/
Ferrous Compounds
/
Adjuvants, Immunologic
/
Dietary Supplements
/
Foot-and-Mouth Disease Virus
/
Aluminum Silicates
/
Foot-and-Mouth Disease
/
Germanium
/
Antibodies, Viral
Limits:
Animals
Language:
English
Journal:
Journal of Veterinary Science
Year:
2014
Type:
Article
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