Clinical Characteristics of Sarcopenia and Cachexia
Journal of Clinical Nutrition
;
: 2-6, 2017.
Article
in Korean
| WPRIM
| ID: wpr-106743
ABSTRACT
Sarcopenia, which is defined as a decrease in skeletal muscle mass and strength with aging, is an important risk factor in clinical medicine that is associated with mortality, and poor surgical and nonsurgical outcomes. Sarcopenia is now recognized as a multifactorial geriatric syndrome. Cachexia is defined as a metabolic syndrome with inflammation as the key feature, so cachexia can be an underlying condition of sarcopenia. Recently, cachexia has been defined as a complex metabolic syndrome associated with an underlying illness and characterized by the loss of muscle mass with or without a loss of fat mass. These two conditions overlap but are not the same. In clinical practice, many factors related to sarcopenia (decreased food intake, inactivity, and decreased hormones) are reported frequently in patients with cachexia. On the contrary, systemic inflammation, the core feature of cachexia, can also be present in apparently healthy older sarcopenic patients. This suggests that new therapeutic approaches, alone or in combination, may be appropriate in both conditions.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Cachexia
/
Aging
/
Clinical Medicine
/
Risk Factors
/
Mortality
/
Muscle, Skeletal
/
Nutrition Therapy
/
Eating
/
Sarcopenia
/
Inflammation
Type of study:
Etiology study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
Korean
Journal:
Journal of Clinical Nutrition
Year:
2017
Type:
Article
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