An Epidemiological Analysis of Hepatitis A Virus Serologic Markers during the Recent Four Years in Korea / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 563-569, 2009.
Article
in Korean
| WPRIM
| ID: wpr-106758
ABSTRACT
BACKGROUND:
To establish effective preventive measures for hepatitis A virus (HAV) infection, a nationwide epidemiologic study on seroprevalence of anti-HAV and the disease prevalence is needed. The aim of this study was to analyze the recent sero-epidemiological changes of hepatitis A markers in Korea.METHODS:
The results of 11,068 anti-HAV total and 32,360 anti-HAV IgM tests by electro-chemiluminescence immunoassay (ECLIA) that had been requested in recent four years (2005-2008) to a reference medical laboratory from 1,699 institutions nationwide were retrospectively analyzed according to the distribution of year, sex, and age groups.RESULTS:
The overall positive rate of anti-HAV total was 62.8%. The overall positive rate of anti-HAV IgM was 11.0%, showing a significantly increasing trend by year 7.7%, 10.9%, 8.9%, and 14.3% in 2005, 2006, 2007, and 2008, respectively (P or =21 yr.Conclusion:
In accordance with a decreasing sero-positivity of anti-HAV total, the prevalence of acute hepatitis A virus infection has been considerably increased during the recent four years in the age groups of > or =21 yr. The results of this study could be used effectively as a basic data for establishing effective preventive measures for hepatitis A including vaccination in these susceptible age groups.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Time Factors
/
Immunoglobulin M
/
Enzyme-Linked Immunosorbent Assay
/
Biomarkers
/
Sex Factors
/
Retrospective Studies
/
Hepatitis A virus
/
Hepatitis A Antibodies
/
Republic of Korea
/
Hepatitis A
Type of study:
Observational study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Korean
Journal:
The Korean Journal of Laboratory Medicine
Year:
2009
Type:
Article
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