Effect of hyperglycemia on mortality rates in critically ill children / 소아과
Korean Journal of Pediatrics
;
: 323-328, 2010.
Article
in Korean
| WPRIM
| ID: wpr-108369
ABSTRACT
PURPOSE:
To verify the effect of hyperglycemia on mortality rates in critically ill children and to identify the blood glucose level that influences prognosis.METHODS:
From July 2006 to June 2008, a total of 206 patients who were admitted to the pediatric intensive care unit (PICU) at Asan Medical Center and who survived for more than 7 days were retrospectively reviewed. We analyzed the maximum glucose value within 7 days in PICU, PRISM-III score and SOFA score within 24 hours, and mortality. We did not perform an adjustment analysis of drugs affecting glucose level.RESULTS:
The maximum glucose level within 7 days in PICU was higher in the nonsurvival group than in the survival group. Using 4 cutoff values (125, 150, 175, and 200 mg/dL), the mortality of patients with hyperglycemia was found to be 13.0%, 14.4%, 19.8%, and 21.1%, respectively, and the cutoff values of 175 and 200 mg/dL revealed significant differences in mortalities between the hyperglycemic and normoglycemic groups. The PRISM-III score was not significantly different between the hyperglycemic and normoglycemic groups under a glucose cutoff value of 175 mg/dL, but the SOFA score was higher in the hyperglycemic group. Under a glucose cutoff value of 200 mg/dL, the PRISM-III score was higher in the hyperglycemic group, and the SOFA score did not differ between the 2 groups.CONCLUSION:
Hyperglycemia with a maximal glucose value > or = 175 mg/dL during the first 7 days after PICU admission was associated with increased mortality in critically ill children.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Blood Glucose
/
Retrospective Studies
/
Critical Illness
/
Glucose
/
Hyperglycemia
/
Intensive Care Units
Type of study:
Observational study
/
Prognostic study
Limits:
Child
/
Humans
Language:
Korean
Journal:
Korean Journal of Pediatrics
Year:
2010
Type:
Article
Similar
MEDLINE
...
LILACS
LIS