Multiple Endocrine Neoplasia and Familial Medullary Thyroid Carcinoma / 대한갑상선학회지
Journal of Korean Thyroid Association
;
: 124-131, 2012.
Article
in Korean
| WPRIM
| ID: wpr-10851
ABSTRACT
Multiple endocrine neoplasia (MEN) is defined as a disorder with neoplasms in two or more different hormonal tissues in several members of a family. MEN1, or Wermer's syndrome, is inherited as an autosomal dominant trait. This syndrome is characterized by neoplasia of the parathyroid glands, enteropancreatic tumors, anterior pituitary adenomas, and other neuroendocrine tumors with variable penetrance. Inherited medullary thyroid carcinoma (MTC) consists of MEN2A, MEN2B, and familial medullary thyroid cancer (FMTC). The identification of hereditary MTC has been facilitated in recent years by direct analysis of germline RET proto-oncogene mutation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Parathyroid Glands
/
Pituitary Neoplasms
/
Thyroid Gland
/
Proto-Oncogenes
/
Multiple Endocrine Neoplasia
/
Thyroid Neoplasms
/
Neuroendocrine Tumors
/
Carcinoma, Medullary
/
Multiple Endocrine Neoplasia Type 2b
/
Multiple Endocrine Neoplasia Type 2a
Type of study:
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Journal of Korean Thyroid Association
Year:
2012
Type:
Article
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