Treatment of the bone marrow failure in the Ho Chi Minh center for hematology and blood transfusion

ABSTRACT

From 1990 to 2000, 513 cases of aplastic anemia were diagnosed and treated in Blood transfusion and Hematology Centre of Ho Chi Minh city, composing of 144 children and 369 adults with 279 males and 234 females. By bone marrow aspiration and biopsy, we diagnosed these cases as follow aplastic anemia 449 cases (87.5%), hypocellularity of bone marrow 45 (8.8%), one lignea hypocellularity of bone marrow 19 (3.7%). From these cases, we have found that - ’s difficult to point out accurately the cause of aplastic anemia and this is still the question for many studies in future. - All the patient was treated mainly blood transfusion, corticoid and androgen (77.5%) with complete and partial response was 25.5%. Besides, 32 cases were treated with corticoid + Sandimum given better results with complete response (32.7%).