Rapid desensitization to isoniazid and rifampin in an adolescent with active pulmonary tuberculosis
Allergy, Asthma & Respiratory Disease
;
: 212-216, 2016.
Article
in Korean
| WPRIM
| ID: wpr-108722
ABSTRACT
Hypersensitivity reactions to antituberculosis medicine are obstacles to the treatment of tuberculosis. However, rapid drug desensitization can secure successful treatment with essential antituberculosis medicines in pediatric patients. A 17-year-old boy with active pulmonary tuberculosis complained of generalized erythematous rashes, pruritus on the 11th day of tuberculosis treatment. He was diagnosed with hypersensitivity reactions to isoniazid and rifampin by the oral provocation test. After desensitization, the patient continued to take antituberculosis treatment with isoniazid, rifampin, pyrazinamide, and ethambutol. We report here a case of successful desensitization in an adolescent with hypersensitivity to isoniazid and rifampin.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pruritus
/
Pyrazinamide
/
Rifampin
/
Tuberculosis
/
Tuberculosis, Pulmonary
/
Desensitization, Immunologic
/
Drug Hypersensitivity
/
Ethambutol
/
Exanthema
/
Hypersensitivity
Limits:
Adolescent
/
Humans
/
Male
Language:
Korean
Journal:
Allergy, Asthma & Respiratory Disease
Year:
2016
Type:
Article
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