Your browser doesn't support javascript.
loading
Type B insulin-resistance syndrome presenting as autoimmune hypoglycemia, associated with systemic lupus erythematosus and interstitial lung disease
The Korean Journal of Internal Medicine ; : 98-102, 2013.
Article in English | WPRIM | ID: wpr-108737
ABSTRACT
We describe an unusual case of systemic lupus erythematosus with pulmonary manifestations presenting as hypoglycemia due to anti-insulin receptor antibodies. A 38-year-old female suffered an episode of unconsciousness and was admitted to hospital where her blood glucose was found to be 18 mg/dL. During the hypoglycemic episode, her serum insulin level was inappropriately high (2,207.1 pmol/L; normal range, 18 to 173) and C-peptide level was elevated (1.7 nmol/L; normal range, 0.37 to 1.47). Further blood tests revealed the presence of antinuclear antibodies, anti-double-stranded DNA antibodies, and anti-Ro/SSA, anti-La/SSB, anti-ribonucleoprotein, and anti-insulin receptor antibodies. A computed tomography scan of the abdomen, aimed at tumor localization, such as an insulinoma, instead revealed ground-glass opacities in both lower lungs, and no abnormal finding in the abdomen. For a definitive diagnosis of the lung lesion, video-associated thoracoscopic surgery was performed and histopathological findings showed a pattern of fibrotic non-specific interstitial pneumonia.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Autoantibodies / Blood Glucose / Insulin Resistance / Receptor, Insulin / Biomarkers / Tomography, X-Ray Computed / Autoimmunity / Treatment Outcome / Lung Diseases, Interstitial / Thoracic Surgery, Video-Assisted Limits: Adult / Female / Humans Language: English Journal: The Korean Journal of Internal Medicine Year: 2013 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Main subject: Autoantibodies / Blood Glucose / Insulin Resistance / Receptor, Insulin / Biomarkers / Tomography, X-Ray Computed / Autoimmunity / Treatment Outcome / Lung Diseases, Interstitial / Thoracic Surgery, Video-Assisted Limits: Adult / Female / Humans Language: English Journal: The Korean Journal of Internal Medicine Year: 2013 Type: Article