Liquid-Based Cytology in Gynecologic Cytology
Korean Journal of Pathology
;
: 291-300, 2009.
Article
in Korean
| WPRIM
| ID: wpr-108872
ABSTRACT
Conventional cervical smears have been a great tool to reduce the incidence of cervical cancer; however, many studies have revealed significant false negative rates. To resolve this problem, the liquid based cytology (LBC) method was developed. The LBC method reduces the number of false positive and false negative smear results because LBC achieves an even distribution of monolayered cells, eliminated the obscuring effects of inflammation and blood. Although the LBC method has many advantages, there are several drawbacks. The LBC method requires an adaptation period for cytopathologists and cytotechnicians. Another drawback is the expense of the method. Thus, the LBC method has been questioned, and criticism has been raised regarding the design of the studies that assert its superiority. With a focus on the cytomorphologic and technical differences of LBC compared with conventional cervical smears, a review of the clinical and cost effectiveness of LBC, a brief comparison of two popular LBC methods, and the basic concepts of study design with respect to LBC are presented in this review.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Vaginal Smears
/
Cervix Uteri
/
Incidence
/
Cost-Benefit Analysis
/
Inflammation
Type of study:
Incidence study
/
Prognostic study
Language:
Korean
Journal:
Korean Journal of Pathology
Year:
2009
Type:
Article
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