Combination pharmacotherapy in lipid management
Journal of the Korean Medical Association
;
: 745-749, 2015.
Article
in Korean
| WPRIM
| ID: wpr-109184
ABSTRACT
Latest guidelines on lipid management recommend statins as the first-line therapy. Because limited evidence is available on cardiovascular outcomes with varying statin-nonstatin combinations, recommendation levels for these regimens have been weak. However, a recent trial has demonstrated the additive effect of the statin-ezetimibe combination. The statin-fibrate combination has shown an effect in certain subgroups and on diabetic microangiopathy. Recent trials using the statin-niacin combination have been largely negative, whereas the statin-omega-3 fatty acids combination demonstrated a positive effect only in one study. Identifying the benefits and limitations of each combination is important for the best possible management of patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Hydroxymethylglutaryl-CoA Reductase Inhibitors
/
Diabetic Angiopathies
/
Drug Therapy
/
Fatty Acids
/
Fibric Acids
/
Ezetimibe
/
Niacin
Type of study:
Practice guideline
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Medical Association
Year:
2015
Type:
Article
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