A 6-year-old girl with vaginal spotting who was diagnosed with perivascular epithelioid cell neoplasm after vaginoscopic resection
Obstetrics & Gynecology Science
;
: 409-411, 2014.
Article
in English
| WPRIM
| ID: wpr-110046
ABSTRACT
Perivascular epithelioid cell neoplasm (PEComa) is a rare tumor with unknown malignant potential. We report a case of a 6-year-old child with history of brain tumor (pineoblastoma), who presented with intermittent vaginal spotting for 6 months. A vaginoscopy revealed a 1.5x1.0-cm mass on the vaginal wall. Pathological examination demonstrated that the tumor was composed of clear cells with organoid patterns, which were immunohistochemically positive for HMB-45 and TFE3, and negative for CK, HNF1-B, SOX10, Melan A, and S-100 protein. These findings were consistent with PEComa arising from the vagina. Regular follow-up with magnetic resonance imaging has shown no signs of recurrence. This case shows that early detection of PEComa and subsequent regular follow-ups are important because of the neoplasm's unknown malignant potential.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Vagina
/
Brain Neoplasms
/
Magnetic Resonance Imaging
/
S100 Proteins
/
Organoids
/
Epithelioid Cells
/
Follow-Up Studies
/
Perivascular Epithelioid Cell Neoplasms
/
MART-1 Antigen
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Screening study
Limits:
Child
/
Female
/
Humans
Language:
English
Journal:
Obstetrics & Gynecology Science
Year:
2014
Type:
Article
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