Pancytopenia Associated with Hypopituitarism in an Acromegaly Patient: A Case Report and a Review of the Literature
Endocrinology and Metabolism
;
: 308-313, 2012.
Article
in English
| WPRIM
| ID: wpr-110107
ABSTRACT
We present the case of a patient with acromegaly who had pancytopenia with hypopituitarism secondary to the excision of a pituitary macroadenoma and radiation therapy. A 28-year-old man presented with pancytopenia and serum electrolyte abnormalities. He was diagnosed with acromegaly and underwent surgery and gamma-knife radiotherapy for a pituitary macroadenoma at the age of 22 years. A recent brain magnetic resonance imaging showed an empty sella, and the basal hormonal profile demonstrated deficiencies of pituitary hormones except thyrotropin. As presenting pancytopenia, his bone marrow biopsy showed hypocellular marrow. The total number of hemocytes increased after hydrocortisone replacement. Hypopituitarism was a possible cause of pancytopenia, and glucocorticoids had crucial effects on converting pancytopenia to normal in this case.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pancytopenia
/
Pituitary Hormones
/
Biopsy
/
Acromegaly
/
Bone Marrow
/
Brain
/
Hydrocortisone
/
Thyrotropin
/
Magnetic Resonance Imaging
/
Glucocorticoids
Limits:
Adult
/
Humans
Language:
English
Journal:
Endocrinology and Metabolism
Year:
2012
Type:
Article
Similar
MEDLINE
...
LILACS
LIS