Histologic Diagnosis of Cervcial Precursor Lesion: Applying the Bethesda System and HPV 16, 18 Correlates / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology
;
: 1056-1061, 2001.
Article
in Korean
| WPRIM
| ID: wpr-110131
ABSTRACT
OBJECT To support the application of the Bethesda classification to the histologic diagnosis of cervical squamous lesions. METHODS:
We evaluated the cervical biopsies and human papilloma virus (HPV) DNA status of 100 clinic patients. The 100 biopsy specimens were analyzed using criteria of the Bethesda system for low-grade squamous intraepithelial lesion(LSIL) and high-grade squamous intraepithelial lesions(HSIL) in association with analysis of HPV DNA virus type by PCR.RESULTS:
By PCR amplified from paraffin embedded tissues, the 40 of 90 cases of classified as HSIL were HPV 16 or 18 positive and 1/10 cases of classified as LSIL was HPV 16 positive.CONCLUSION:
This study supports the usefullness of certain histologic criteria of the Bethesda system for distinguishing squamous intraepithelial lesions into two grades.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Papilloma
/
Paraffin
/
Biopsy
/
DNA
/
Cervix Uteri
/
Polymerase Chain Reaction
/
Classification
/
Diagnosis
/
DNA Viruses
/
Human papillomavirus 16
Type of study:
Diagnostic study
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Obstetrics and Gynecology
Year:
2001
Type:
Article
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