Association between carotid intima-media thickness and Ankle-Brachial Index in patients with ischemic stroke / 동물의과학연구지
Journal of Biomedical Research
;
: 68-71, 2014.
Article
in Korean
| WPRIM
| ID: wpr-110212
ABSTRACT
BACKGROUND AND PURPOSE:
The Ankle-Brachial Index (ABI) is the ratio of blood pressure in the lower legs to that in the arms. The intima-media thickness (IMT) of extracranial carotid arteries determined by B-mode ultrasound is a measurable index of the presence of atherosclerosis. A low ABI and a high carotid IMT are independently related to increased risk of cardiovascular events. This study examined the association between carotid IMT and ABI in patients with ischemic stroke. MATERIALS ANDMETHODS:
Retrospectively, 116 hospitalized patients with ischemic stroke were recruited. Using a pulse wave velocity ABI device along with carotid duplex sonography, we measured carotid IMT and ABI and investigated the correlation between average values.RESULTS:
There was a significant difference in carotid IMT between the normal and abnormal ABI groups (P=0.0262). The group with an abnormal ABI was more than five times as likely to have increased carotid IMT as the group with a normal ABI (age, sex-adjusted OR 5.67 (95% CI 1.85~17.38)). The ABI and carotid IMT showed a weak inverse linear correlation in patients with ischemic stroke (correlation coefficient -0.378 after adjusting for age and sex).CONCLUSION:
Our study suggests that an abnormal ABI is associated with a high carotid IMT in patients with ischemic stroke.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arm
/
Blood Pressure
/
Carotid Arteries
/
Retrospective Studies
/
Ultrasonography
/
Stroke
/
Atherosclerosis
/
Ankle Brachial Index
/
Carotid Intima-Media Thickness
/
Pulse Wave Analysis
Type of study:
Diagnostic study
/
Observational study
/
Risk factors
Limits:
Humans
Language:
Korean
Journal:
Journal of Biomedical Research
Year:
2014
Type:
Article
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