Evaluation of a Rapid Immunochromatographic Assay Kit for the Diagnosis of Salmonella Typhi Infection / 대한임상미생물학회지
Korean Journal of Clinical Microbiology
;
: 123-127, 2007.
Article
in Korean
| WPRIM
| ID: wpr-110612
ABSTRACT
BACKGROUND:
Widal test, whose sensitivity and specificity are variable from region to region depending on the incidence of typhoid fever, is still in use and shows a relatively low positive predictive value in Korea. We evaluated a rapid immunochromatographic assay (ICA) kit for the rapid diagnosis of Salmonella Typhi infection.METHODS:
Twenty five patients with Salmonella Typhi bacteremia were selected for the patient group. For the control group, 21 nontyphoidal salmonellosis patients, 56 non-Salmonella bacteremia patients, and 57 healthy individuals were selected for evaluating the specificity of ICA test. Each serum specimen was tested with the SD Salmonella Typhi IgG/IgM kits (Standard Diagnostics, Inc., Yongin, Korea).RESULTS:
The ICA showed a sensitivity of 100% in Salmonella Typhi patients, and specificities of 61.9%, 82.1% and 91.2% in nontyphoidal salmonellosis patients, non-Salmonella bacteremia patients, and healthy individuals, respectively. The ICA test showed a high sensitivity but a low specificity when compared with the Widal test.CONCLUSION:
The ICA test by SD Salmonella Typhi IgG/IgM kit is highly sensitive, but its specificity is relatively low. The ICA test is simple, objective, and suitable for screening typhoid fever.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Salmonella
/
Salmonella Infections
/
Salmonella typhi
/
Typhoid Fever
/
Mass Screening
/
Incidence
/
Chromatography, Affinity
/
Sensitivity and Specificity
/
Bacteremia
/
Diagnosis
Type of study:
Diagnostic study
/
Incidence study
/
Prognostic study
/
Screening study
Limits:
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Journal of Clinical Microbiology
Year:
2007
Type:
Article
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