Transfusion Strategy of RhD-negative/variant Patients in the Korean Population
Laboratory Medicine Online
;
: 89-93, 2017.
Article
in Korean
| WPRIM
| ID: wpr-110645
ABSTRACT
The prevalence of RhD-negative individuals in the Korean population is approximately 0.15-0.30% and the supply of RhD-negative blood often faces potential shortage. Furthermore, 15-17% of serologically RhD-negative Korean individuals were revealed to be DEL variants and should be treated as RhD-positive when being considered as blood donors. This change is expected to result in a further shortage of RhD-negative blood supply, whereas surplus DEL variant blood stock is created. Therefore, it is now required to amend blood donation and supply policies, and transfusion strategies. In this review, a new transfusion strategy for patients with RhD-negative or variant blood in Korea is discussed, with particular interest in women of child-bearing age, patients with anti-D, and Asia type DEL (c.1227G>A) variants.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Asia
/
Blood Donors
/
Prevalence
/
Korea
Type of study:
Prevalence study
Limits:
Female
/
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Laboratory Medicine Online
Year:
2017
Type:
Article
Similar
MEDLINE
...
LILACS
LIS