A case of angioedema associated with losartan / 천식및알레르기
Journal of Asthma, Allergy and Clinical Immunology
;
: 95-98, 2003.
Article
in Korean
| WPRIM
| ID: wpr-110739
ABSTRACT
Angioedema is a non-pitting edema that occurs in the skin and mucus membranes. It is known that major etiologies include hereditary deficiency of C1 esterase inhibitor, temperature extreme, trauma, food sensitivity, and medications such as penicillin, aspirin, NSAIDS and ACE inhibitors. ACE inhibitors are blocking the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, and increasing local levels of bradykinin, a potent vasodilator. This increased bradykinin has been theorized to cause angioedema and cough in patients on ACE inhibitors. However, there has been very few causes of angioedema induced by angiotensin II receptor blocker. This is the first report of a patient presenting angioedema induced by losartan -angiotensin II receptor blocker- in this century.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Penicillins
/
Skin
/
Angiotensin I
/
Angiotensin II
/
Bradykinin
/
Receptors, Angiotensin
/
Angiotensin-Converting Enzyme Inhibitors
/
Anti-Inflammatory Agents, Non-Steroidal
/
Aspirin
/
Losartan
Limits:
Humans
Language:
Korean
Journal:
Journal of Asthma, Allergy and Clinical Immunology
Year:
2003
Type:
Article
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