Postnatal exposure to a progestin does not prevent uterine adenogenesis in domestic dogs
Journal of Veterinary Science
;
: 111-113, 2016.
Article
in English
| WPRIM
| ID: wpr-110758
ABSTRACT
To assess the effects of a single supraphysiological postnatal administration of a progestogen on uterine glands in dogs, 10 females were randomly assigned to a medroxyprogesterone acetate 35 mg (MPA; n = 6) or placebo (n = 4) group within the first 24 h of birth. The safety of the treatment was also evaluated. A transient mild clitoris enlargement appeared in MPA-treated females. Microscopic postpubertal uterine assessment revealed the presence of uterine glands in all cases without significant differences in the area occupied by the glands per µm2 of endometrium nor in the height of the uterine epithelium.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Organ Size
/
Sexual Maturation
/
Uterus
/
Random Allocation
/
Clitoris
/
Medroxyprogesterone Acetate
/
Epithelium
/
Animals, Newborn
Limits:
Animals
Language:
English
Journal:
Journal of Veterinary Science
Year:
2016
Type:
Article
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