Effects of testicular biopsy in rat testis: comparison of open surgical percutaneous needle and biopsy gun biopsy technique / 대한비뇨기과학회지

ABSTRACT

Testicular biopsy has been known as useful diagnostic tool for the male infertility. Open biopsy and percutaneous needle biopsy have been widely used. Recently. Biopty gun method has been applied in the testicular biopsy. These three different biopsy methods were performed in rats to compare the diagnostic accuracy and effects on spermatogenesis. Diagnostic accuracy was not compromised owing to different biopsy methods but the seminiferous tubules obtained by testicular biopsy were most abundant in the open biopsy and sparse in the Biopty gun biopsy. Using the spermatogenesis index, such as sperm head count and repopulation index, all biopsy techniques were not harmful to spermatogenesis. These results demonstrate that needle biopsy of the testis with Biopty gun system is rapid, effective an8 safe way to obtain a testicular biopsy.