Corticobasal Degeneration Presenting as Non-Fluent/Agrammatic Primary Progressive Aphasia: A Case Report
Dementia and Neurocognitive Disorders
;
: 55-58, 2016.
Article
in English
| WPRIM
| ID: wpr-11101
ABSTRACT
BACKGROUND:
Non-fluent agrammatic primary progressive aphasia (naPPA) is characterized by progressive non-fluent speech disorder and might be associated with taupathy such as corticobasal degeneration (CBD) and progressive supranuclear palsy. We report a case of overlap syndrome presented with language impairment, and diagnosed as naPPA with possible CBD. CASE REPORT A 58-year-old woman visited a memory and dementia clinic, with a 10-month history of progressive language disturbance. She was diagnosed as naPPA and overlapping CBD, based on the clinical features and neuroimaging findings including florbetaben PET.CONCLUSIONS:
naPPA is pathologically caused by taupathy, and might progress to asymmetrical parkinsonism and apraxia, suggestive of CBD. Overlapping clinical features in our case represent various phenotypes of taupathy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Apraxias
/
Phenotype
/
Supranuclear Palsy, Progressive
/
Aphasia, Primary Progressive
/
Parkinsonian Disorders
/
Dementia
/
Neuroimaging
/
Memory
Limits:
Female
/
Humans
Language:
English
Journal:
Dementia and Neurocognitive Disorders
Year:
2016
Type:
Article
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