Leukoencephalopathy and Akinetic Mutism in a Married Couple: A Probable Association with Oriental Medicine
Journal of Clinical Neurology
;
: 223-226, 2011.
Article
in English
| WPRIM
| ID: wpr-111084
ABSTRACT
BACKGROUND:
Oriental medicines have been associated with severe psychiatric, neurological, and other adverse medical events. These medicines occasionally cause a typical reversible toxic encephalopathy, but most such cases are not recognized because these adverse events are complex and are associated with other systemic signs and symptoms. CASE REPORT We describe a married couple with rapid progressive cognitive impairment and akinetic mutism after taking the same oriental medicines on the same day. Brain magnetic resonance images of the couple showed typical leukoencephalopathy in the periventricular white matter and basal ganglia regions, bilaterally.CONCLUSIONS:
The development of neurobehavioral symptoms and toxic leukoencephalopathy in both patients following the ingestion of oriental medicines is suggestive of a cause-and-effect association, although such a relationship needs to be verified.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Basal Ganglia
/
Brain
/
Magnetic Resonance Spectroscopy
/
Neurotoxicity Syndromes
/
Akinetic Mutism
/
Eating
/
Leukoencephalopathies
/
Medicine, East Asian Traditional
Limits:
Humans
Language:
English
Journal:
Journal of Clinical Neurology
Year:
2011
Type:
Article
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