Anorectal Manometric Dysfunctions in Newly Diagnosed, Early-Stage Parkinson's Disease
Journal of Clinical Neurology
;
: 184-189, 2012.
Article
in English
| WPRIM
| ID: wpr-11127
ABSTRACT
BACKGROUND AND PURPOSE:
Anorectal dysmotility is common in advanced Parkinson's disease (PD), but there have been few evaluations in newly diagnosed PD patients.METHODS:
We conducted anorectal manometric evaluations in 19 newly diagnosed, drug-naive, early-stage PD patients. All of the PD patients were questioned regarding the presence of anorectal symptoms.RESULTS:
Anorectal manometry was abnormal in 12 of the 19 patients. These abnormalities were more common in patients with more severe anorectal symptoms, as measured using a self-reported scale. However, more than 40% of patients with no or minimal symptoms also exhibited manometric abnormalities.CONCLUSIONS:
These results suggest that anorectal dysmotility manifests in many early-stage PD patients, which this represent evidence for the involvement of neuronal structures in such nonmotor manifestations in PD.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Parkinson Disease
/
Manometry
/
Neurons
Type of study:
Diagnostic study
Limits:
Humans
Language:
English
Journal:
Journal of Clinical Neurology
Year:
2012
Type:
Article
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