Early Satiety Is the Only Patient-Reported Symptom Associated With Delayed Gastric Emptying, as Assessed by Breath-Test
Journal of Neurogastroenterology and Motility
;
: 61-66, 2011.
Article
in English
| WPRIM
| ID: wpr-111703
ABSTRACT
BACKGROUND/AIMS:
To evaluate associations between delayed gastric emptying (GE) assessed by the octanoic acid breath test and upper gastrointestinal (GI) symptoms.METHODS:
A historical, prospective study included 111 consecutive symptomatic adults referred for a GE breath test because of upper abdominal symptoms suggestive of delayed GE. Exclusion criteria included underlying organic disease associated with delayed GE. Patients completed a symptom questionnaire and underwent a GE octanoic breath test. Patients with delayed GE were compared with those with normal results, for upper GI symptoms.RESULTS:
Early satiety was the only symptom significantly associated with delayed GE. It was observed in 52% of subjects with delayed GE compared to 33% patients with no evidence of delayed GE (P = 0.005). This association was seen for all degrees of severity of delayed GE. Patients with early satiety had a t1/2 of 153.9 +/- 84.6 minutes compared to 110.9 +/- 47.6 minutes in subjects without it (P = 0.002). In a logistic regression model, early satiety was significantly associated with delayed GE (OR, 2.29; 95% CI, 1.01-5.18; P = 0.048).CONCLUSIONS:
Early satiety is the only patient-reported GI symptom associated with delayed GE. The utility of GE tests as a clinical diagnostic tool in the work-up of dyspeptic symptoms may be overrated.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Breath Tests
/
Caprylates
/
Logistic Models
/
Prospective Studies
/
Surveys and Questionnaires
/
Dyspepsia
/
Gastric Emptying
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Humans
Language:
English
Journal:
Journal of Neurogastroenterology and Motility
Year:
2011
Type:
Article
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