Effects of Diuretics on Serum and Urinary Electrolytes in Patients with Hypertension
Korean Circulation Journal
;
: 263-270, 1986.
Article
in Korean
| WPRIM
| ID: wpr-112082
ABSTRACT
In order to investigate electrolyte changes in serum and urine diuretic therapy, we studied 98 patients with hypertension not optimally controlled by previous treatment. After we divied the patients into three gorups in randomized trial, group A were given Amiloride 10mg/day, group B were given Dihydrochlorothiazide 50mg/day, group C were given Amiloride 5mg/day combined with Dihydrochlorothiazide 25mg/day for 7 days. Blood pressure and electrolyte changes in serum and urine after diuretic theraphy for 7 days were as follows. 1) Serum sodium concentrations were not significantly changed in all three groups(P>0.05). 2) Serum potassium concentrations were increased in group A and C (P<0.05), but there were no significant changes in group B(P<0.05). 3) Urinary sodium exceretions were increased in all three groups(P<0.05). 4) Urinary potassium excretion were decreased in group A and C (P<0.05), but there were increased in group B (P<0.05). 5) Blood pressure were decreased in all three groups(P<0.05).
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Potassium
/
Sodium
/
Blood Pressure
/
Diuretics
/
Electrolytes
/
Amiloride
/
Hydrochlorothiazide
/
Hypertension
Type of study:
Controlled clinical trial
Limits:
Humans
Language:
Korean
Journal:
Korean Circulation Journal
Year:
1986
Type:
Article
Similar
MEDLINE
...
LILACS
LIS